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Annual Review of Pharmacology and Toxicology
Volume 50, February 2010
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Contents and Authors
Allosteric Receptors: From Electric Organ to Cognition,
Jean-Pierre Changeux
Pharmacogenetics of Drug Dependence: Role of Gene Variations in Susceptibility and Treatment,
Jibran Y. Khokhar,
Charmaine S. Ferguson,
Andy Z.X. Zhu,
Rachel F. Tyndale
Close Encounters of the Small Kind: Adverse Effects of Man-Made Materials Interfacing with the Nano-Cosmos of Biological Systems,
Anna A. Shvedova,
Valerian E Kagan,
Bengt Fadeel
GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies,
Joël Bockaert,
Julie Perroy,
Carine Bécamel,
Philippe Marin,
Laurent Fagni
The c-MYC NHE III1: Function and Regulation,
Verónica González,
Laurence H. Hurley
The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer,
Denis Drygin,
William G. Rice,
Ingrid Grummt
LPA Receptors: Subtypes and Biological Actions,
Ji Woong Choi,
Deron R. Herr,
Kyoko Noguchi,
Yun C. Yung,
Chang-Wook Lee,
Tetsuji Mutoh,
Mu-En Lin,
Siew T. Teo,
Kristine E. Park,
Alycia N. Mosley,
Jerold Chun
The Role of Clock Genes in Pharmacology,
Georgios K. Paschos,
Julie E. Baggs,
John B. Hogenesch,
Garret A. FitzGerald
Toxicological Disruption of Signaling Homeostasis: Tyrosine Phosphatases as Targets,
James M. Samet,
Tamara L. Tal
Discovery and Development of Therapeutic Aptamers,
P. R. Bouchard,
R. M. Hutabarat,
K. M. Thompson
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform,
C. Frank Bennett,
Eric E. Swayze
Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease,
Colleen M. Niswender,
P. Jeffrey Conn
Mechanisms of Cell Protection by Heme Oxygenase-1,
Raffaella Gozzelino,
Viktoria Jeney,
Miguel P. Soares
Epac: Defining a New Mechanism for cAMP Action,
Martijn Gloerich,
Johannes L. Bos
Circadian Timing in Cancer Treatments,
Francis Lévi,
Alper Okyar,
Sandrine Dulong,
Pasquale F. Innominato,
Jean Clairambault
Economic Opportunities and Challenges for Pharmacogenomics,
Patricia A. Deverka,
John Vernon,
Howard L. McLeod
Tissue Renin-Angiotensin-Aldosterone Systems: Targets for Pharmacological Therapy,
Michael Bader
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ISSN: 0362-1642
ISBN: 978-0-8243-0450-8
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Editor
Arthur K. Cho
University of California, Los Angeles
Associate Editors
Terrence F. Blaschke
Stanford University School of Medicine
Paul A. Insel
University of California, San Diego, School of Medicine
Horace H. Loh
University of Minnesota Medical School
Committee Members
Judy Bolton
University of Illinois at Chicago
Gary L. Johnson
University of North Carolina, Chapel Hill
Debra Laskin
Rutgers University
Urs A. Meyer
University of Basel
Gerald Miwa
Victor Hruby, Guest
University of Arizona, Tucson
Production
Editor
Nina Perry
(650) 843-6662
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