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Contents and Authors

Preface

The Power of One, James E. Rothman

Prefatory Article

From Virus Structure to Chromatin: X-ray Diffraction to Three-Dimensional Electron Microscopy, Aaron Klug

Recent Advances in Biochemistry

Genomic Screening with RNAi: Results and Challenges, Stephanie Mohr, Chris Bakal, Norbert Perrimon

Nanomaterials Based on DNA, Nadrian C. Seeman

Eukaryotic Chromosome DNA Replication: Where, When, and How? Hisao Masai, Seiji Matsumoto, Zhiying You, Naoko Yoshizawa-Sugata, Masako Oda

Regulators of the Cohesin Network, Bo Xiong, Jennifer L. Gerton

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases, Nima Mosammaparast, Yang Shi

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway, Michael R. Lieber

The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation, Aaron Klug

Origins of Specificity in Protein-DNA Recognition, Remo Rohs, Xiangshu Jin, Sean M. West, Rohit Joshi, Barry Honig, Richard S. Mann

Transcript Elongation by RNA Polymerase II, Luke A. Selth, Stefan Sigurdsson, Jesper Q. Svejstrup

Biochemical Principles of Small RNA Pathways, Qinghua Liu, Zain Paroo

Functions and Regulation of RNA Editing by ADAR Deaminases, Kazuko Nishikura

Regulation of mRNA Translation and Stability by microRNAs, Marc Robert Fabian, Nahum Sonenberg, Witold Filipowicz

Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome, Joachim Frank, Ruben L. Gonzalez, Jr.

Adding New Chemistries to the Genetic Code, Chang C. Liu, Peter G. Schultz

Bacterial Nitric Oxide Synthases, Brian R. Crane, Jawahar Sudhamsu, Bhumit A. Patel

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective, Olga Khersonsky, Dan S. Tawfik

Hydrogenases from Methanogenic Archaea, Nickel, a Novel Cofactor, and H₂ Storage, Rudolf K. Thauer, Anne-Kristin Kaster, Meike Goenrich, Michael Schick, Takeshi Hiromoto, Seigo Shima

Copper Metallochaperones, Nigel J. Robinson, Dennis R. Winge

High-Throughput Metabolic Engineering: Advances in Small-Molecule Screening and Selection, Jeffrey A. Dietrich, Adrienne E. McKee, Jay D. Keasling

Botulinum Neurotoxin: A Marvel of Protein Design, Mauricio Montal

Chemical Approaches to Glycobiology, Laura L. Kiessling, Rebecca A. Splain

Cellulosomes: Highly Efficient Nanomachines Designed to Deconstruct Plant Cell Wall Complex Carbohydrates, Carlos M.G.A. Fontes, Harry J. Gilbert

Somatic Mitochondrial DNA Mutations in Mammalian Aging, Nils-Göran Larsson

Physical Mechanisms of Signal Integration by WASP Family Proteins, Shae B. Padrick, Michael K. Rosen

Amphipols, Nanodiscs, and Fluorinated Surfactants: Three Nonconventional Approaches to Studying Membrane Proteins in Aqueous Solutions, Jean-Luc Popot

Protein Sorting Receptors in the Early Secretory Pathway, Julia Dancourt, Charles Barlowe

Virus Entry by Endocytosis, Jason Mercer, Mario Schelhaas, Ari Helenius

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ISSN: 0066-4154
ISBN: 978-0-8243-0879-7

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