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Contents and Authors

The Role of Gß? Subunits in the Organization, Assembly, and Function of GPCR Signaling Complexes, Denis J. Dupré, Mélanie Robitaille, R. Victor Rebois, Terence E. Hébert

Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics, Neal L. Benowitz

Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology, Alan L. Schwartz, Aaron Ciechanover

Progress in Genetic Studies of Pain and Analgesia, Michael L. LaCroix-Fralish, Jeffrey S. Mogil

Lipid Mediators in Health and Disease: Enzymes and Receptors as Therapeutic Targets, Takao Shimizu

Sorting out Astrocyte Physiology from Pharmacology, Todd A. Fiacco, Cendra Agulhon, Ken D. McCarthy

Lithium's Antisuicidal Efficacy: Elucidation of Neurobiological Targets Using Endophenotype Strategies, Colleen E. Kovacsics, Irving I. Gottesman, Todd D. Gould

Global and Site-Specific Quantitative Phosphoproteomics: Principles and Applications, Boris Macek, Matthias Mann, Jesper V. Olsen

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy, Sanjeev Shangary, Shaomeng Wang

Epigenetics, DNA Methylation, and Chromatin Modifying Drugs, Moshe Szyf

The COXIB Experience: A Look in the Rearview Mirror, Lawrence J. Marnett

Quantitative Disease, Drug, and Trial Models, Jogarao Gobburu, Lawrence J. Lesko

Immunodrugs:Therapeutic VLP-Based Vaccines for Chronic Diseases, Gary Jennings, Martin F. Bachmann

Akt/GSK3 Signaling in the Action of Psychotropic Drugs, Jean-Martin Beaulieu, Raul R. Gainetdinov, Marc G. Caron

Topical Microbicides to Prevent HIV: Clinical Drug Development Challenges, Craig W. Hendrix, Ying Jun Cao, Edward J. Fuchs

Emerging Pharmacology: Inhibitors of Human Immunodeficiency Virus Integration, Daria Hazuda, Marian Iwamoto, Larissa Wenning

The TRPC Class of Ion Channels: A Critical Review of Their Roles in Slow, Sustained Increases in Intracellular Ca2+ Concentrations, Lutz Birnbaumer

Mycobacterial Subversion of Chemotherapeutic Reagents and Host Defense Tactics: Challenges in Tuberculosis Drug Development, Liem Nguyen, Jean Pieters

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ISSN: 0362-1642
ISBN: 978-0-8243-0449-7

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